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Our recombinant antibodies are designed to target therapy-relevant domains—the same regions recognized by therapeutic antibodies, ADCs, and CAR T-cells. The highly conformational epitopes bound by these therapeutics are usually lost during formalin fixation and antigen retrieval. In contrast, our antibodies bind linear epitopes within the same domains, enabling reliable detection in FFPE tissue and making them ideal for IHC-based biomarker research.
Each antibody is a recombinant monoclonal rabbit IgG with domain-specific binding validated in IHC on FFPE samples and/or ELISA-based profiling.
Linear epitopes in the same domains recognized by therapeutic antibodies and CAR-Ts.
Reliable IHC performance using standard fixation and antigen retrieval protocols.
Monoclonal rabbit IgGs produced
recombinantly for lot-to-lot consistency
See how our domain-specific antibodies enable multiplexed IHC to visualize the co-expression and spatial heterogeneity of drug targets within the same tumor sample.
Using our IHC-validated antibodies in multiplex panels, researchers can investigate multiple therapy-relevant targets within the same FFPE section while preserving spatial context. This allows for detailed visualization of co-expression patterns, mutual exclusivity, and the distribution of drug targets across distinct tumor cell subpopulations, providing insights that are not accessible through bulk or single-marker analyses.
We offer high-quality staining, imaging, and reporting using our domain specific antibodies—ideal for biomarker profiling across tumor panels.
We offer scalable IHC and multiplex staining services using one or more of our antibodies. This service is ideal for projects that require analysis across large sample sets, such as biomarker profiling across different tumor entities or validation of domain-specific expression patterns.
We provide staining, imaging, and result reporting on customer-supplied or commercially sourced FFPE tissue sections.
For more information or to get started, please reach out to us at info@epitopelabs.com or use the contact form. Our team will respond promptly to assist with your inquiry and provide the information you need. We look forward to hearing from you.
Recombinant monoclonal rabbit antibodies targeting clinically relevant extracellular domains. Validated for IHC on FFPE
tissue and ELISA-based profiling.
Let us stain and analyze your samples.
We offer IHC services using one or more
of our antibodies to reveal spatial patterns
and co-expression in tissue panels.
Binds Domain III of HER3, the extracellular region targeted by therapeutic antibodies like Patritumab Deruxtecan and Lumretuzumab.
Binds Domain III of HER3, the extracellular region targeted by therapeutic antibodies like Patritumab Deruxtecan and Lumretuzumab.
Binds Domain III of HER3, the extracellular region targeted by therapeutic antibodies like Patritumab Deruxtecan and Lumretuzumab.
